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Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
Published on: July 17, 2012
Cadmium-free quantum dots as time-gated bioimaging probes in highly-autofluorescent human breast cancer cells
Gopa Mandal1, Molly Darragh, Y Andrew Wang
1Department of Chemistry and Biochemistry, University of Arkansas, 345 N. Campus Drive, Fayetteville, AR 72701, USA.
Chemical Communications (Cambridge, England)
|December 11, 2012
Abstract:
We report cadmium-free, biocompatible (Zn)CuInS(2) quantum dots with long fluorescence lifetimes as superior bioimaging probes using time-gated detection to suppress cell autofluorescence and improve the signal : background ratio by an order of magnitude. These results will be important for developing non-toxic fluorescence imaging probes for ultrasensitive biomedical diagnostics.
