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Tooth pulp changes following Le Fort I maxillary osteotomy in a primate model
R M Browne1, C L Brady, J W Frame
1Department of Oral Surgery and Oral Pathology, Birmingham Dental School.
The British Journal of Oral & Maxillofacial Surgery
|February 1, 1990
Summary
Le Fort I maxillary osteotomy can cause significant tooth pulp disturbances, including cell degeneration and necrosis, in animal models. Careful monitoring is essential to understand these effects in human patients.
Area of Science:
- Oral and Maxillofacial Surgery
- Dental Research
- Animal Models in Surgery
Background:
- Le Fort I osteotomy is a surgical procedure for maxillary advancement.
- Potential effects on dental pulp vitality are a concern following this procedure.
Purpose of the Study:
- To histologically evaluate the effects of Le Fort I maxillary osteotomy with advancement on tooth pulp vitality in a rhesus monkey model.
Main Methods:
- Fifteen adult rhesus monkeys underwent Le Fort I maxillary osteotomy with 8 mm advancement.
- Forty-five tooth pulps were examined histologically at intervals from 0 to 24 weeks post-surgery.
Main Results:
- 47% of examined pulps showed marked cellular changes, with 31% exhibiting cell degeneration and 16% showing necrosis.
- Features included inflammation (13%) and reactive dentine formation (24%).
- Axonal degeneration was observed initially, with recovery by 24 weeks.
Conclusions:
- Le Fort I maxillary osteotomy can induce pulpal disturbances in an animal model.
- The clinical significance and extent of these pulpal effects in human patients require careful monitoring.