Opium intoxication in an infant on Indian folk medicine

Ira Shah1

  • 1Department of Pediatrics, B. J. Wadia Hospital for Children, Parel, Mumbai, India.

Insights

A baby boy experienced drowsiness after his mother administered herbal remedies. Opium seeds in the herbs were identified as the cause, leading to opium and benzodiazepine detection in the child.

Area of Science:

  • Pediatrics
  • Clinical Toxicology
  • Pharmacology

Background:

  • Herbal remedies are widely used for perceived health benefits in infants.
  • Accidental toxicity from improperly prepared or contaminated herbal products is a concern.
  • Assessing the safety of traditional remedies in pediatric populations is crucial.

Observation:

  • A 45-day-old infant presented with acute onset of increased drowsiness.
  • Maternal administration of a multi-herb mixture for 15 days preceded the infant's symptoms.
  • Urine toxicology screening identified the presence of opium and benzodiazepines.

Findings:

  • Opium seeds were identified within the herbal mixture administered to the infant.
  • The detected opium and benzodiazepines in the infant's urine were directly linked to the herbal preparation.
  • The infant's symptoms resolved spontaneously without specific medical intervention or antidote administration.

Implications:

  • This case highlights the potential for serious adverse events from herbal products containing controlled substances.
  • Healthcare providers should inquire about the use of all substances, including herbal remedies, in pediatric cases of altered mental status.
  • Further research is needed to ensure the safety and accurate labeling of herbal products intended for infant use.

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