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Diazo Compounds as Highly Tunable Reactants in 1,3-Dipolar Cycloaddition Reactions with Cycloalkynes()

Nicholas A McGrath1, Ronald T Raines

  • 1Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706, USA.

Chemical Science
|December 11, 2012
PubMed
Summary

Diazo compounds are versatile in 1,3-dipolar cycloaddition reactions. Their reactivity, tunable via solvent and predictable by molecular orbital energies, offers new bio-orthogonal chemistry strategies.

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