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Related Concept Videos

Positron Emission Tomography01:29

Positron Emission Tomography

Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body being...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy

Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

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Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
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A hand-held beta imaging probe for FDG.

Bipin Singh1, Brendan C Stack, Samta Thacker

  • 1Radiation Monitoring Devices, Inc., Watertown, MA 02472, USA.

Annals of Nuclear Medicine
|December 12, 2012
PubMed
Summary
This summary is machine-generated.

A novel Imaging Beta Probe™ (IBP™) provides real-time surgical visualization of beta-emitting radiopharmaceuticals like (18)FDG. This handheld device aids in precisely locating and confirming tumor excision, improving surgical outcomes.

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Area of Science:

  • Nuclear medicine
  • Surgical oncology
  • Medical imaging technology

Background:

  • Intraoperative gamma probes are increasingly used in surgery.
  • Current probes lack imaging capabilities, limiting ancillary information of the surgical area.
  • A need exists for advanced imaging tools to enhance surgical precision.

Purpose of the Study:

  • To develop and validate a novel, hand-held digital Imaging Beta Probe™ (IBP™).
  • To enable real-time imaging of beta-emitting radiopharmaceuticals during surgery.
  • To improve spatial resolution, sensitivity, and convenience compared to existing instruments.

Main Methods:

  • Design and construction of a hand-held digital beta probe.
  • Validation of the probe as a visual mapping device.
  • Testing in an animal model using (18)FDG-avid lesions.

Main Results:

  • Demonstrated successful generation of beta images from (18)FDG-avid lesions in an animal model.
  • The Imaging Beta Probe™ (IBP™) provided higher spatial resolution and sensitivity.
  • The device proved convenient for surgical use.

Conclusions:

  • Imaging beta irradiation is feasible in animal cancer models using (18)FDG.
  • This technology holds potential for clinical intraoperative tumor mapping.
  • Visual depiction of malignancy can assist surgeons in lesion localization and excision.