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Updated: May 16, 2026

A Murine Model of a Burn Wound Reconstructed with an Allogeneic Skin Graft
Published on: August 8, 2020
Severe adult burn survivors. What information about skin allografts?
Sonia Gaucher1, Nathalie Duchange, Mohamed Jarraya
1Laboratoire d'éthique médicale et médecine légale, Université Paris Descartes, Sorbonne Paris Cité, EA 4569, 45 rue des Saints-Pères, 75006, Paris, France, sonia.gaucher@cch.aphp.fr.
Abstract:
During the acute phase of a severe burn, surgery is an emergency. In this situation, human skin allografts constitute an effective temporary skin substitute. However, information about the use of human tissue can not be given to the patients because most of the allografted patients are unconscious due to their injury. This study explored the restitution of information on skin donation to patients who have been skin allografted and who have survived their injury. A qualitative study was conducted due to the limited number of patients in ability to be interviewed according to our medical and psychological criteria. 12 patients who had been treated between 2002 and 2008 were interviewed. Our results show that 10 of them ignored that they had received skin allografts. One of the two patients who knew that they had received allografts knew that skin had been harvested from deceased donor. All patients expressed that there is no information that should not be delivered. They also expressed their relief to have had the opportunity to discuss their case and at being informed during their interview. Their own experience impacted their view in favor of organ and tissue donation.
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