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Related Experiment Video

Updated: May 16, 2026

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

Would you rather be ill now, or later?

Arthur E Attema¹, Matthijs M Versteegh

¹Health Economics, Erasmus University Rotterdam, The Netherlands.

Health Economics

|December 12, 2012

Summary

This summary is machine-generated.

New time tradeoff (TTO) methods, lead time TTO and lag time TTO, address classic TTO issues. Individuals prefer delayed illness, showing higher discount rates for longer health state durations.

Keywords:

TTO discounting lag time TTO lead time TTO time preference

Related Experiment Videos

Last Updated: May 16, 2026

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

A Mouse Model for the Transition of Streptococcus pneumoniae from Colonizer to Pathogen upon Viral Co-Infection Recapitulates Age-Exacerbated Illness

Published on: September 28, 2022

Area of Science:

Health Economics
Decision Analysis
Biostatistics

Background:

The time tradeoff (TTO) method is crucial for calculating quality-adjusted life years (QALYs), impacting medical intervention benefit assessments.
Classic TTO faces methodological challenges, leading to the development of 'lead time' TTO and 'lag time' TTO.

Purpose of the Study:

To leverage the temporal properties of lead and lag time TTO to estimate implied discounting parameters.
To analyze how the timing of health states influences individual preferences and discount rates.

Main Methods:

Utilized data from a prior study that implemented lead and lag time TTO.
Estimated implied discounting parameters based on individuals' choices regarding the timing of health states.

Main Results:

Demonstrated that individuals exhibit a preference for experiencing ill-health at a later time rather than immediately.
Found that discount rates increase with longer durations of health states, indicating a greater preference for avoiding prolonged periods of illness.

Conclusions:

Lead and lag time TTO methods offer valuable insights into temporal preferences in health valuation.
The findings have implications for economic evaluations of healthcare interventions, particularly concerning the timing of benefits and risks.