A case of mitral valve tophus in a patient with severe gout tophaceous arthritis

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An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

Atooshe Rohani1, Soheila Chamanian, Peiman Hosseinzade

  • 1Cardiac Research Center, Emam Reza Hospital, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Journal of Clinical Imaging Science
|December 12, 2012
PubMed

Insights

Gout can affect heart valves, with a rare case showing a mitral valve tophus. Echocardiography revealed a hyperechoic mass, confirming gouty arthritis involvement of the cardiac valve.

Area of Science:

  • Cardiology
  • Rheumatology
  • Pathology

Background:

  • Cardiac valve tophi are rare, with limited case reports in medical literature.
  • Gout, a form of inflammatory arthritis, typically affects joints but can have systemic manifestations.

Observation:

  • This case report details a patient with severe tophaceous gout arthritis.
  • Echocardiography identified a hyperechoic mass on the posterior leaflet of the mitral valve.
  • The mitral valve ring remained intact despite the presence of the mass.

Findings:

  • The echocardiographic features, combined with severe gouty arthritis, strongly suggested the diagnosis of a gout tophus on the mitral valve.
  • This finding represents a rare instance of cardiac involvement in severe gout.

Implications:

  • Highlights the importance of considering systemic conditions like gout in cardiac diagnoses.
  • Suggests echocardiography can be a valuable tool in identifying cardiac tophi.
  • Underscores the potential for urate crystal deposition in cardiac structures in severe gout.

Keywords:
Arthritisechocardiogramgoutmitral valvetophus

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