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Updated: May 16, 2026

Novel Percutaneous Approach for Deployment of 3D Printed Coronary Stenosis Implants in Swine Models of Ischemic Heart Disease
Published on: February 18, 2020
[More than 25 years of coronary stent implantation]
Joost Daemen1, Robert Jan van Geuns, Felix Zijlstra
1Erasmus Medisch Centrum, afd. Thoraxcentrum, Rotterdam, the Netherlands.
Insights
Percutaneous coronary intervention (PCI) with stenting is common for acute coronary syndrome in the Netherlands. Innovations make complex stenoses treatable with PCI, requiring optimal stent and medication choices.
Area of Science:
- Cardiovascular Medicine
- Interventional Cardiology
Context:
- Approximately 38,000 percutaneous coronary interventions (PCI) are performed annually in the Netherlands.
- Stent implantation occurs in about 90% of these PCI procedures.
- PCI is primarily used for acute coronary syndrome, with decreasing use for stable coronary disease.
Purpose:
- To assess the increasing accessibility of PCI for complex stenoses due to technological advancements.
- To determine the optimal combination of stent type and antiplatelet therapy for improved treatment durability.
- To inform clinical decisions regarding stent implantation through a combination of functional and anatomical stenosis measurements.
Summary:
- Modern coated stents significantly enhance treatment durability, with only 7% requiring repeat procedures within a year.
- Innovations in techniques and equipment are expanding the applicability of PCI to complex stenoses previously treated with coronary bypass surgery.
- Informed decisions on stent implantation necessitate integrating both functional and anatomical stenosis assessments.
Impact:
- Improved patient outcomes through more durable PCI treatments.
- Reduced need for coronary bypass surgery for complex stenoses.
- Ongoing clinical studies aim to optimize stent selection and antiplatelet regimens for percutaneous coronary intervention.
Abstract:
The number of Dutch patients undergoing percutaneous coronary intervention (PCI) currently comprises approximately 38,000 cases a year; a stent is implanted in approximately 90% of cases. About two-thirds of these patients undergo PCI for acute coronary syndrome; the number of patients treated for stable coronary disease is gradually decreasing. The modern coated stents improve the durability of treatment considerably: 7% require a repeat procedure after 1 year. Complex stenoses, which were usually treated with coronary bypass surgery in the past, are becoming more accessible to PCI due to current innovations and improvements in techniques and equipment. A combination of functional and anatomical measurements of a stenosis is needed to make an informed decision about whether or not to implant a stent. A large number of clinical studies are currently being conducted for the purpose of identifying the most optimal combination of a stent and platelet-aggregation inhibitors.
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