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Lymphoepithelial carcinoma in the maxillary sinus: a case report
Darouichi Mohammed1, Alshammari Jaber, Monnier Philippe
1Department of ORL and Head and Neck surgery, CHUV, Lausanne, Switzerland. Kishore.Sandu@hopitalvs.ch.
Journal of Medical Case Reports
|December 13, 2012
Summary
A rare lymphoepithelial carcinoma of the maxillary sinus was diagnosed in a patient presenting with epistaxis. This case highlights the diagnostic challenges and successful management of this uncommon malignancy.
Area of Science:
- Otorhinolaryngology
- Oncology
- Pathology
Background:
- Lymphoepithelial carcinoma of the maxillary sinus is an exceptionally rare malignancy.
- Pre-operative diagnosis of this condition poses significant challenges.
Purpose of the Study:
- To report a case of lymphoepithelial carcinoma of the maxillary sinus.
- To discuss the diagnostic and management strategies for this rare tumor.
Main Methods:
- A 72-year-old woman presented with epistaxis and a maxillary sinus mass.
- Diagnosis was established via transnasal endoscopic biopsy and confirmed by histology.
- Treatment involved radical excision followed by post-operative radiotherapy.
Main Results:
- Histopathology confirmed lymphoepithelial carcinoma, with negative Epstein-Barr virus assays.
- The patient remained disease-free at a three-year follow-up.
- The tumor was successfully excised, and radiotherapy contributed to a favorable outcome.
Conclusions:
- Accurate diagnosis requires a high index of suspicion and comprehensive patho-immunological testing.
- This case underscores the importance of multidisciplinary management for rare head and neck cancers.
- Effective treatment can lead to long-term disease control for maxillary sinus lymphoepithelial carcinoma.