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Updated: May 16, 2026

Single-throughput Complementary High-resolution Analytical Techniques for Characterizing Complex Natural Organic Matter Mixtures
Published on: January 7, 2019
Determining and reporting purity of organic molecules: why qNMR
Shivani Mahajan1, Inder Pal Singh
1Department of Natural Products, National Institute of Pharmaceutical Education and Research, SAS Nagar, Punjab, India.
Abstract:
Although NMR has been routinely used to determine/estimate relative number of protons for structure elucidation, it has been rarely used to determine and report the purity of organic compounds. Through this paper, we want to emphasize on routine use of quantitative NMR (qNMR) for this purpose. The results of qNMR can be routinely considered as documentation of purity much like other established methods (HPLC, elemental analysis and differential scanning calorimetry). qNMR is a fast, easy, accurate and non-destructive alternate to speed up the whole analytical process and serves the purpose of both identification and purity determination of compounds using single technique.
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