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A brief review of biomarkers for preventing and treating cardiovascular diseases

Xiaolun Sun1, Zhenquan Jia

  • 1Department of Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.

Journal of Cardiovascular Disease Research
|December 13, 2012
PubMed

Insights

This review highlights key cardiac biomarkers for diagnosing cardiovascular diseases, including mean platelet volume and hyperhomocysteinemia. These markers aid in assessing disease pathogenesis and patient outcomes.

Area of Science:

  • Cardiology
  • Clinical Diagnostics
  • Biomarker Research

Background:

  • Cardiovascular diseases (CVDs) represent a significant global health burden.
  • Biomarkers are crucial for evaluating health status and diagnosing diseases.
  • Cardiac biomarkers are essential for understanding CVD pathogenesis and diagnosis.

Purpose of the Study:

  • To review major biomarkers used in recent clinical research for diagnosing cardiovascular diseases.
  • To focus on specific biomarkers including mean platelet volume, hyperhomocysteinemia, serum magnesium, microalbuminuria, and QT interval abnormalities.
  • To highlight findings from clinical case reports in this issue.

Main Methods:

  • Literature review of recent clinical research on cardiovascular disease biomarkers.
  • Focus on specific diagnostic markers: mean platelet volume, hyperhomocysteinemia, serum magnesium, microalbuminuria, QT interval prolongation, and dispersion.
  • Analysis of clinical case report-based studies.

Main Results:

  • Mean platelet volume, hyperhomocysteinemia, serum magnesium, microalbuminuria, and QT interval abnormalities are key diagnostic indicators.
  • These biomarkers offer objective measures for assessing CVD pathogenesis.
  • Clinical case reports provide practical insights into biomarker application.

Conclusions:

  • The discussed biomarkers are valuable tools for diagnosing cardiovascular diseases.
  • Accurate measurement of these biomarkers aids in patient management and treatment strategies.
  • Further research and clinical application of these biomarkers are encouraged.

Keywords:
Biomarkerscardiovascular diseasespathogenesis

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