Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type II Diabetes Mellitus III: Clinical Manifestations and Diagnosis

Type 2 diabetes mellitus develops gradually and is often asymptomatic in early stages.Clinical ManifestationsWhen symptoms appear, they include fatigue, blurred vision, pruritus, delayed wound healing, and recurrent infections, particularly candidal infections. Peripheral neuropathy may present as numbness or tingling in the extremities. Classic hyperglycemia symptoms—polyuria, polydipsia, and polyphagia—are less common. Most patients are overweight and frequently have associated hypertension...

Diabetes: Management and Pharmacotherapy

Diabetes: Management and Pharmacotherapy

The therapy for diabetes aims to alleviate hyperglycemia-related symptoms, prevent acute metabolic decompensation, and reduce chronic end-organ complications. Glycemic control is evaluated through short-term (self-monitoring, continuous glucose monitoring) and long-term (A1c, fructosamine) metrics, enabling near real-time tracking of blood glucose levels and reflecting glycemic control over specific time frames.
Insulin remains the cornerstone of treatment for most patients with type 1 and many...

Type II Diabetes I: Introduction

Type II Diabetes I: Introduction

Type 2 diabetes mellitus (T2DM) is a chronic metabolic disorder characterized by insulin resistance, in which target tissues such as the liver, muscle, and adipose tissue respond poorly to insulin. It is also associated with inadequate compensatory insulin secretion, where pancreatic β-cells fail to produce sufficient insulin. Together, these abnormalities lead to persistent hyperglycemia.EtiologyT2DM develops through a complex interaction of genetic predisposition and environmental or...

Preventive Healthcare Services

Preventive Healthcare Services

Preventive healthcare services keep people healthy via frequent check-ups, screening, and counseling. They primarily aid in disease prevention rather than treating an acute or chronic illness. Preventive treatment also keeps individuals productive and energetic, allowing them to work well into their retirement years. Examples of preventive care services include:

Diabetes: Symptoms, Diagnosis, and Complications

Diabetes: Symptoms, Diagnosis, and Complications

For most patients, experiencing several weeks of polyuria, polydipsia, fatigue, and significant weight loss may indicate the presence of diabetes. Furthermore, adults displaying the phenotypic appearance of type 2 diabetes (particularly those who are obese and not initially insulin-requiring), may have islet cell autoantibodies, suggesting autoimmune-mediated β cell destruction and a diagnosis of latent autoimmune diabetes of adults (LADA). The categorization of glucose homeostasis is based on...

Diabetes Mellitus: Type 2 and Gestational

Diabetes Mellitus: Type 2 and Gestational

Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Dr-MUSIC: An Effective Device for Investigating Multisensory Mechanisms during Development with EEG recordings<sup></sup>.

Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference·2023

Same author

The hesitancy in the nutritional prevention.

Annali di igiene : medicina preventiva e di comunita·2023

Same author

The "Nutritional Prevention" within Italy's National Prevention Plan 2020-25.

Annali di igiene : medicina preventiva e di comunita·2023

Same author

Age, Sex, Hypertension and HDL-C Alter Serum BACE1 Activity in Cognitively Normal Subjects: Implications for Alzheimer's Disease.

The journal of prevention of Alzheimer's disease·2022

Same author

Impact of Built Environment and Neighborhood on Promoting Mental Health, Well-being, and Social Participation in Older People: an Umbrella Review.

Annali di igiene : medicina preventiva e di comunita·2022

Same author

Relation between blood pressure and genito-urinary symptoms in the years across the menopausal age.

Climacteric : the journal of the International Menopause Society·2022

Search research articles

Related Experiment Video

Updated: May 16, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Diabetes screening in primary care: the PRE.DI.CO. study.

G Bonaccorsi¹, S Guarducci, E Ruffoli

¹Department of Public Health, University of Florence, Italy.

Annali Di Igiene : Medicina Preventiva E Di Comunita

|December 14, 2012

Summary

The Finnish Diabetes Risk Score (FINDRISC) effectively identifies individuals at high risk for type 2 diabetes in primary care settings. This screening tool aids in early detection and intervention for diabetes prevention efforts worldwide.

Related Experiment Videos

Last Updated: May 16, 2026

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

A High-Throughput Multiplexed Screening for Type 1 Diabetes, Celiac Diseases, and COVID-19

Published on: July 5, 2022

Area of Science:

Public Health
Epidemiology
Preventive Medicine

Background:

Global rise in type 2 diabetes prevalence necessitates effective screening tools.
The PRE.DI.CO project aimed to identify individuals at high risk for type 2 diabetes or undiagnosed cases.
Early detection of diabetes risk is crucial for public health interventions.

Purpose of the Study:

To evaluate the effectiveness of the Finnish Diabetes Risk Score (FINDRISC) questionnaire in identifying individuals at risk for type 2 diabetes.
To assess the prevalence of diabetes risk factors and newly diagnosed diabetes within a specific population.
To determine the applicability of FINDRISC in a primary care setting.

Main Methods:

Administered the FINDRISC questionnaire to 658 subjects aged 35-70 years.
Calculated European Heart Score for cardiovascular risk using anamnestic data.
Conducted oral glucose tolerance tests (OGTT) for high-risk individuals.

Main Results:

45.3% low risk, 33.1% moderate risk, 17.0% high risk, 4.9% very high risk based on FINDRISC.
Newly diagnosed diabetes found in 14.5% of subjects; 30.6% had Impaired Glucose Fasting (IFG).
Higher FINDRISC scores correlated with increased 10-year cardiovascular disease mortality risk.

Conclusions:

The FINDRISC questionnaire is a valid tool for identifying diabetes risk in primary care.
The study demonstrates the practical application of FINDRISC in a real-world setting.
Early identification of at-risk individuals can facilitate timely interventions for type 2 diabetes.