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Solitary rectal ulcer syndrome in children: a literature review
Seyed Mohsen Dehghani1, Abdorrasoul Malekpour, Mahmood Haghighat
1Gastroenterohepatology Research Center, Shiraz Transplant Research Center, Nemazee Teaching Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz 71937-11351, Iran. dehghanism@sums.ac.ir
Insights
Solitary rectal ulcer syndrome (SRUS) is a chronic rectal disorder often misdiagnosed in children. Current treatments for this benign condition are suboptimal, leading to persistent symptoms like rectal bleeding.
Area of Science:
- Gastroenterology
- Pediatric Gastroenterology
Background:
- Solitary rectal ulcer syndrome (SRUS) is a chronic, benign disorder affecting the rectum.
- It is commonly seen in young adults but less frequently diagnosed in children, often presenting with rectal bleeding, mucus discharge, and incomplete defecation.
- SRUS is frequently associated with prolonged straining and abnormal defecation patterns.
Purpose of the Study:
- To review the current diagnostic approaches for Solitary Rectal Ulcer Syndrome (SRUS).
- To discuss the various treatment modalities available for SRUS, highlighting their effectiveness and limitations.
- To emphasize the challenges in diagnosing and managing SRUS in pediatric populations.
Main Methods:
- Literature review of existing studies on Solitary Rectal Ulcer Syndrome (SRUS).
- Analysis of clinical presentations, diagnostic criteria (endoscopic and histological), and treatment outcomes.
- Focus on pediatric cases and their unique diagnostic and therapeutic considerations.
Main Results:
- SRUS diagnosis relies on clinical symptoms, endoscopic visualization, and histological examination.
- Current treatment strategies, including conservative management and topical therapies, often yield suboptimal outcomes.
- Pediatric SRUS, though uncommon, poses significant morbidity due to persistent symptoms, particularly rectal bleeding.
Conclusions:
- Effective management of SRUS requires a thorough understanding of its pathophysiology and presentation.
- There is a need for improved diagnostic accuracy and more effective treatment protocols, especially for pediatric patients.
- Further research is warranted to optimize therapeutic strategies for Solitary Rectal Ulcer Syndrome to improve patient outcomes.
Abstract:
Solitary rectal ulcer syndrome (SRUS) is a benign and chronic disorder well known in young adults and less in children. It is often related to prolonged excessive straining or abnormal defecation and clinically presents as rectal bleeding, copious mucus discharge, feeling of incomplete defecation, and rarely rectal prolapse. SRUS is diagnosed based on clinical symptoms and endoscopic and histological findings. The current treatments are suboptimal, and despite correct diagnosis, outcomes can be unsatisfactory. Some treatment protocols for SRUS include conservative management such as family reassurance, regulation of toilet habits, avoidance of straining, encouragement of a high-fiber diet, topical treatments with salicylate, sulfasalazine, steroids and sucralfate, and surgery. In children, SRUS is relatively uncommon but troublesome and easily misdiagnosed with other common diseases, however, it is being reported more than in the past. This condition in children is benign; however, morbidity is an important problem as reflected by persistence of symptoms, especially rectal bleeding. In this review, we discuss current diagnosis and treatment for SRUS.
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