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Updated: Sep 30, 2026

Mouse Models Of Helicobacter Infection And Gastric Pathologies
Published on: October 18, 2018
Immunostaining of antral gastrin cells is quantitatively increased in Heliobacter pylori gastritis
E A Sankey1, P A Helliwell, A P Dhillon
1Department of Histopathology, Royal Free Hospital, London, UK.
Abstract:
The amount of gastrin-like immunostaining in gastrin (G) cells of the antral mucosa was quantified using a computer-assisted method of measuring immunoreaction product. Biopsies from 25 patients without Heliobacter-like organisms and 60 patients with varying degrees of infection were immunostained for gastrin. Twenty-five G cells from each patient were measured both subjectively and by image analysis. Gastrin-like immunoreactivity was found to be significantly increased in the presence of Heliobacter-like organisms.
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