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Updated: May 16, 2026

A Swine Model of Neonatal Asphyxia
Published on: October 11, 2011
Time to achieve stable pulse oximetry values in VLBW infants in the delivery room
Bheru Gandhi1, Wade Rich, Neil Finer
1Division of Neonatology, UCSD Medical Center, University of California, San Diego, CA, USA.
Objective:
To study the time needed to obtain a reliable, functioning pulse oximeter signal during the resuscitation of very low birth weight (VLBW) infants.
Methods:
This is a retrospective review of data from the resuscitation of preterm, VLBW infants at the University of California, San Diego Medical Center. Resuscitation teams consisted of a neonatal physician, a nurse, and respiratory therapist. Pulse oximetry was routinely used in all preterm deliveries. During resuscitation, the respiratory therapist attempted to place a pulse oximeter probe on the right hand or wrist immediately after birth. The BioPAC MP-150 Data Acquisition System was used to record analog data during the resuscitation, including the SpO2 value. From the analog tracing, the time at which a reliable pulse oximetry signal was obtained was determined.
Results:
50 VLBW (≤1500 g) preterm patients were studied. Mean gestational age was 27+4 weeks (range: 23-35 weeks). Mean birth weight was 920±287 g (range: 360-1445 g). Mean time to achieve functioning pulse oximetry was 79±42 s (range: 40-240 s). The median time was 67 s (interquartile range: 50-93 s). 86% of infants had a reliable SpO2 value obtained prior to 120 s of life.
Conclusions:
Our data show that an experienced respiratory therapist can apply a pulse oximeter and achieve reliable SpO2 values for the majority VLBW infants by 120 s of life as recommended by current NRP guidelines.
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