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Updated: May 16, 2026

Fetal Mouse Cardiovascular Imaging Using a High-frequency Ultrasound (30/45MHZ) System
Published on: May 5, 2018
Effects of maternal smoking on fetal organs
Abdulbaki Karaoglu1, Turan Tunc, Gokhan Aydemir
1Gulhane Military Medical Faculty, Department of Pediatrics, Ankara, Turkey. akaraoglu@gata.edu.tr
Background:
Unfavorable effects of in-utero smoke exposure have been shown in several studies.
Objectives:
In this experimental study, the authors aimed at showing detrimental effects of cigarette smoke on fetal tissues by assessing apoptosis that is detected by performing TUNEL staining.
Material And Methods:
Designed groups were smoke exposed rats before and during pregnancy and control groups. Rat offsprings were sacrificed when they were 12 days old.
Results:
Lung, kidney, adrenal and gonad tissues were harvested for histopathologic analysis and assessed by TUNEL (Terminal dUTP Nick End Labeling) staining.
Conclusions:
Smoke exposure caused increased apoptotic activity in lung parenchyma of study groups.
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