Related Experiment Video
Updated: May 16, 2026

Quantification of Levator Ani Hiatus Enlargement by Magnetic Resonance Imaging in Males and Females with Pelvic Organ Prolapse
Published on: April 17, 2019
Prolapse and sexual function in women with benign joint hypermobility syndrome
H Mastoroudes1, I Giarenis1, L Cardozo1
1King's College Hospital NHS Foundation Trust, London, UK.
Objective:
To determine whether pelvic organ prolapse (POP) and sexual dysfunction are more severe in women with benign joint hypermobility syndrome (BJHS) than in the normal population.
Design:
Case-control study.
Setting:
King's College Hospital NHS Foundation Trust, London, UK and University College Hospital, London, UK.
Population:
Women diagnosed with BJHS (n = 60) at University College Hospital. Control participants (n = 60) recruited from King's College Hospital NHS Foundation Trust.
Methods:
Objective assessment of POP was undertaken using the Pelvic Organ Prolapse Quantification System (POP-Q). Both groups were asked to complete the Prolapse quality of life (P-QOL) and pelvic organ prolapse/urinary incontinence sexual (PISQ-12) questionnaires.
Main Outcome Measures:
Comparison of vaginal anatomy using POP-Q between the two groups. Comparison of P-QOL and PISQ-12 quality of life scores between the two groups.
Results:
In all, 120 women (60 in Study group, 60 in Control group) were recruited. All women in the study group were matched with healthy control women according to age, parity and ethnicity. There was a statistically significant difference between points Aa, Ba, Ap, Bp and C in study and control groups showing that prolapse is objectively more severe in those with BJHS. Significantly more women with BJHS felt that POP interfered with sex and defecation compared with the control group. The impact of prolapse symptoms on quality of life was statistically different in almost all nine P-QOL domains.
Conclusions:
A large number of women with BJHS have prolapse symptoms, which significantly affect their quality of life. POP is more severe in women with BJHS.
Related Concept Videos
Mitral Valve Prolapse II: Assessment and Management
Degenerative Disc Disease ll: Pathophysiology
Mitral Valve Prolapse I: Introduction
Degenerative Disc Disease I: Introduction
Mitral Valve Prolapse III: Nursing Management
Disorders of the Female Reproductive System

