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Related Concept Videos

Cancer Vaccines01:30

Cancer Vaccines

Cancer treatment vaccines are a rapidly evolving field that offers a promising approach to immunotherapy. Unlike traditional vaccines that prevent diseases, cancer treatment vaccines are designed to treat existing cancers by stimulating the immune system to recognize and attack cancer cells.
Cancer vaccines come in two categories: preventive (prophylactic) and treatment (active). Preventive vaccines, such as the Human Papillomavirus (HPV) vaccine, protect against viruses that cause certain...
Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists01:28

Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates these...
Cancer Therapies02:49

Cancer Therapies

Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
Cancer02:18

Cancer

Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...
Chemotherapy-Induced Nausea and Vomiting: Cannabinoids01:21

Chemotherapy-Induced Nausea and Vomiting: Cannabinoids

Tetrahydrocannabinol (THC) is a phytocannabinoid that primarily interacts with the CB1 receptor, a type of G protein-coupled receptor (GPCR) predominantly in and around the chemoreceptor trigger zone (CTZ) and emetic center. THC also blocks the serotonin receptor activity in the dorsal vagal complex (DVC) by inhibiting serotonin release. THC exerts its anti-emetic effects through these interactions, which are beneficial for patients undergoing chemotherapy.
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Related Experiment Video

Updated: May 16, 2026

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production
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Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production

Published on: October 6, 2023

Snake venom: a potent anticancer agent.

Deepika Jain1, Sudhir Kumar

  • 1IGNOU-I2IT Centre of Excellence for Advanced Education and Research, Pune, Maharashtra, India.

Asian Pacific Journal of Cancer Prevention : APJCP
|December 19, 2012
PubMed
Summary
This summary is machine-generated.

Snake venom offers a promising source for novel anticancer drugs, addressing limitations of traditional chemotherapy like resistance. Research explores these natural compounds for future cancer treatment development.

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Last Updated: May 16, 2026

Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production
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Captive Maintenance and Venom Extraction of Tityus serrulatus (Brazilian Yellow Scorpion) for Antivenom Production

Published on: October 6, 2023

Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation
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Potentiation of Anticancer Antibody Efficacy by Antineoplastic Drugs: Detection of Antibody-drug Synergism Using the Combination Index Equation

Published on: January 19, 2019

Area of Science:

  • Oncology
  • Biochemistry
  • Pharmacology

Background:

  • Cancer remains a leading global cause of death, necessitating innovative treatment strategies.
  • Conventional chemotherapy faces challenges with patient non-response and acquired drug resistance.
  • Natural products, particularly from diverse sources like animal venoms, are increasingly explored for therapeutic potential.

Purpose of the Study:

  • To review the anticancer potential of molecules derived from snake venom.
  • To highlight snake venom components as a source for novel anticancer drug development.
  • To discuss the current status and future prospects of snake venom-derived anticancer agents.

Main Methods:

  • Literature review of scientific publications on snake venom and cancer research.
  • Analysis of studies investigating the cytotoxic and antitumor effects of snake venom components.
  • Examination of preclinical and clinical data for snake venom-derived anticancer compounds.

Main Results:

  • Snake venoms contain a variety of bioactive molecules with demonstrated anticancer properties.
  • Several snake venom components exhibit selective toxicity towards cancer cells, with varying mechanisms of action.
  • Some snake venom-derived compounds are currently undergoing clinical trials for cancer therapy.

Conclusions:

  • Snake venom represents a rich and underexplored reservoir for the discovery of new anticancer drugs.
  • Further research and development of snake venom-derived molecules could lead to effective treatments for chemoresistant cancers.
  • Clinical translation of these natural compounds holds promise for advancing cancer pharmacotherapy.