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Updated: May 15, 2026

How to Study Placebo Responses in Motion Sickness with a Rotation Chair Paradigm in Healthy Participants
Published on: December 14, 2014
The placebo effect: why we should care
Francisco Tausk1, Robert Ader, Nana Duffy Smith
1Department of Dermatology University of Rochester School of Medicine and Dentistry, Box 697, Rochester, NY 14642, USA. francisco_tausk@URMC.Rochetser.edu
Abstract:
Contrary to its definition, a placebo is far from an inert substance but carries meaningful responses that can mediate significant outcome results in pharmacotherapeutic studies. The advent of detailed studies and modern imaging techniques have provided the basis to understand the underlying mechanisms of the placebo effect, as well as its localization to determined brain centers. Designing clinical trials using principles of classical conditioning to mediate placebo effects may enhance treatment outcomes and provide novel pharmacotherapeutic modalities.
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