Related Experiment Video
Updated: May 15, 2026
Dual Test Gas Pulmonary Diffusing Capacity Measurement During Exercise in Humans Using the Single-Breath Method
Published on: February 2, 2024
[The Study of Health in Pomerania (SHIP) reference values for cardiopulmonary exercise testing]
S Gläser1, T Ittermann, C Schäper
1Klinik für Innere Medizin B - Kardiologie, Pneumologie/Infektiologie Intensivmedizin und Weaningzentrum, Universitätsmedizin Greifswald. sven.glaeser@uni-greifswald.de
Abstract:
The interpretation of gas exchange measured by cardiopulmonary exercise testing (CPET) depends on reliable reference values. Within the population based Study of Health in Pomerania (SHIP) CPET was assessed in 1706 volunteers. The assessment based on symptom limited exercise tests on a bicycle in a sitting position according to a modified Jones protocol. CPET was embedded in an extensive examination program. After the exclusion of active smokers and volunteers with evidence of cardiopulmonary and musculoskeletal disorders the reference population comprised 616 healthy subjects (333 women) aged 25 to 85 years. Reference equations including upper and/or lower limits based on quantile regression were assessed. All values were corrected for the most important influencing factors.This study provides reference equations for gas exchange and exercise capacity assessed within a population in Germany.
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