Related Experiment Video
Updated: May 15, 2026

Systems Analysis of the Neuroinflammatory and Hemodynamic Response to Traumatic Brain Injury
Published on: May 27, 2022
Impact of trauma system development on pediatric injury care
David P Mooney1, Ivan M Gutierrez, Qiaoli Chen
1Trauma Program, Department of Surgery, Children's Hospital Boston and Harvard Medical School, 300 Longwood Avenue, Fegan 3, Boston, MA 02115, USA. David.Mooney@childrens.harvard.edu
Insights
Trauma systems reduce childhood injury hospitalizations and improve triage of severely injured children to trauma centers. However, they did not significantly impact overall injury death rates or triage to trauma centers for all injured children.
Area of Science:
- Pediatric Trauma Care
- Public Health Systems
- Injury Prevention and Control
Background:
- Trauma systems aim to improve survival for severely injured patients by facilitating rapid transport to specialized trauma centers.
- The effectiveness of trauma systems in pediatric populations, particularly regarding triage and mortality, requires ongoing evaluation.
Purpose of the Study:
- To analyze the impact of trauma systems on pediatric triage practices and injury mortality rates.
- To compare hospitalization and death rates for injured children in states with and without established trauma systems.
Main Methods:
- A population-based study analyzed data from 58,583 injured children (<15 years) hospitalized in New England (1996-2006).
- Compared outcomes between three states with trauma systems and three states without.
- Examined trends in trauma center admissions for all injured, severely injured, and brain-injured children, alongside hospitalization and mortality rates.
Main Results:
- Injury hospitalization rates decreased in both trauma system and non-trauma system states, but decreased more rapidly in states with trauma systems.
- No significant difference in overall injury death rates was observed between states with and without trauma systems.
- Trauma systems increased the proportion of severely injured and brain-injured children admitted to trauma centers, with a more rapid increase observed in trauma system states.
Conclusions:
- Trauma systems are effective in reducing childhood injury hospitalization rates.
- They improve the likelihood of severely injured and brain-injured children being admitted to appropriate trauma centers.
- While improving triage for critical pediatric injuries, trauma systems did not significantly alter overall injury mortality rates in this study.
Purpose:
Trauma systems improve survival by directing severely injured patients to trauma centers. This study analyzes the impact of trauma systems on pediatric triage and injury mortality rates.
Methods:
Population-based data were collected on injured children less than 15 years who were admitted to any hospital in New England from 1996 to 2006. Data from three trauma system states were compared to three non-trauma system states. The percentages of injured children, severely injured children, and brain-injured children admitted to trauma centers were determined as well as injury hospitalization and death rates. Time trend analysis examined the pace of change between the groups.
Results:
A total of 58,583 injured children were hospitalized during the study period. Injury hospitalization rates were initially similar between the two groups (with and without trauma systems) and decreased over time in both. Rates decreased more rapidly in trauma system states compared to those without, (P = 0.003). Injury death rates decreased over time in both groups with no difference between the groups, (P = 0.20). A higher percentage of injured children were admitted to trauma centers in non-trauma system states throughout the study period, and this percentage increased in both groups of states. A higher percentage of severely injured children and brain-injured children were admitted to trauma centers in non-trauma system states and both percentages increased over time. The increase was more rapid in trauma system states for children with severe injuries (P < 0.001) and children with brain injuries (P < 0.001).
Discussion:
Trauma systems decreased childhood injury hospitalization rates and increased the percentage of severely injured children and brain-injured children admitted to trauma centers. Mortality and overall triage rates were unaffected.
More Related Videos
Related Concept Videos
Traumatic Brain Injury l: Introduction
Acute Kidney Injury V: Interprofessional Care
Spinal Cord Injury ll: Pathophysiology
Aneurysm III: Interprofessional Care
Post-traumatic Stress Disorder
Symptoms and Behavioral Manifestations
A spectrum of distressing symptoms characterizes PTSD. Recurrent flashbacks, where individuals involuntarily relive traumatic events, are a...

