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Updated: May 15, 2026
High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
[Study on chemical constituents from the root bark of Tripterygium hypoglaucum]
Fu-Gui Xie1, Chuang-Jun Li, Jing-Zhi Yang
1State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China. xiefugui01@163.com
Objective:
To study the chemical constituents of the root bark of Tripterygium hypoglaucum.
Methods:
Column chromatography was used to separate the chemical constituents. The structures were determined by application of spectroscopic (NMR, MS) and chemical methods.
Results:
Eleven compounds were isolated and identified as 4'-0-(-) methylepigallocatechin (1),3,4-dimethoxyphenyl-beta-D-glucopyranoside (2), 3,4,5-trimethoxyphenyl-f-D-glucopyranoside (3), (2R,3R)-3,5,7,3',5'-pentahydroxyflavan (4), 2-O-deacetyleuonine (5), tripfordine C (6), peritassine A (7) hypoglaunine C (8), wilfortrine (9), wilforgine (10) and wilfordine (11).
Conclusion:
Compounds 1-6 are isolated from this plant for the first time.
