Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Computed Tomography

Computed Tomography

Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...

Imaging Studies III: Computed Tomography

Imaging Studies III: Computed Tomography

DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...

Assessment of Diffusion and Perfusion

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Deep learning-based Desikan-Killiany parcellation of the brain using diffusion MRI.

Scientific reports·2026

Same author

Subthalamic segmentations in relation to deep brain stimulation volumes in Parkinson's disease.

Acta neurochirurgica·2026

Same author

No link between piriform cortex subregion resection and seizure freedom in two cohorts with temporal lobe epilepsy.

Journal of neurology·2026

Same author

Optimized precision oncology through implementation of a comprehensive molecular analysis pipeline - relevance for additional therapeutic options.

Cancer genetics·2026

Same author

Aromatic amino acid metabolism shapes autophagy-mediated adaptation to iron deprivation in glioblastoma cells.

Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine·2026

Same author

Comprehensive protocol for mixed reality visualization and navigation using 3D Slicer.

PloS one·2026

Same journal

Electric-Scooters: An Emerging Source of High-Severity Pediatric Head Trauma.

Neurosurgery·2026

Same journal

Survival After Surgery for Spinal Osteosarcoma and the Role of Chemotherapy and Treatment Sequencing: A National Cohort Multivariable Analysis.

Neurosurgery·2026

Same journal

Safety and Efficacy of 3-Month Versus 6-Month Duration of Dual Antiplatelet Therapy in Pipeline Embolization Treatment of Intracranial Aneurysms.

Neurosurgery·2026

Same journal

Risk Factors of Revision Surgery After Acute Proximal Junctional Fracture Following Adult Spinal Deformity Surgery.

Neurosurgery·2026

Same journal

Sensorimotor Network Alterations and Compensation in Cervical Spondylotic Myelopathy: A 7 T Task-Based and Resting-State Functional MRI Study.

Neurosurgery·2026

Same journal

Hyperselective Peripheral Neurectomy Versus Medical Therapy for Refractory Poststroke Spasticity: A Randomized Controlled Trial.

Neurosurgery·2026

See all related articles

Search research articles

Related Experiment Video

Updated: May 15, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Fiber tractography based on diffusion tensor imaging compared with high-angular-resolution diffusion imaging with

Daniela Kuhnt¹, Miriam H A Bauer, Jan Egger

¹Department of Neurosurgery, University of Marburg, Marburg, Germany.

|December 21, 2012

Summary

This summary is machine-generated.

High-angular-resolution diffusion imaging with compressed sensing (HARDI+CS) improves fiber tractography, offering better visualization of complex brain pathways near tumors and edema. This advanced technique enhances clinical neuroimaging by overcoming limitations of traditional diffusion tensor imaging.

More Related Videos

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Related Experiment Videos

Last Updated: May 15, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression

Published on: May 7, 2019

Area of Science:

Neuroimaging
Diffusion MRI techniques
Computational anatomy

Background:

Diffusion Tensor Imaging (DTI) tractography faces limitations in resolving complex fiber structures like crossing fibers and in areas affected by tumors or edema.
High-Angular-Resolution Diffusion Imaging (HARDI) offers superior resolution for complex fiber pathways.
Compressed Sensing (CS) enables faster HARDI acquisitions, making it more feasible for clinical use.

Observation:

This study investigated the efficacy of HARDI combined with CS (HARDI+CS) for fiber tractography.
The research focused on patients with gliomas near critical language areas, comparing HARDI+CS with traditional DTI methods.
Functional MRI was used to identify cortical language sites for precise anatomical correlation.

Findings:

HARDI+CS tractography consistently produced more compact and accurate fiber bundles compared to DTI.
In 3 out of 6 patients, HARDI+CS successfully traced neuroanatomically plausible pathways obscured by tumor and edema on DTI.
The sylvian fissure's complex curvature was accurately depicted by HARDI+CS in all cases, versus only 2 with DTI.

Implications:

HARDI+CS tractography demonstrates significant potential for improving the visualization of intricate neural pathways in clinical neuroimaging.
This technique offers a viable solution for overcoming the resolution limitations of DTI in pathological conditions and complex white matter regions.
The reduced acquisition time associated with CS further supports the clinical applicability of HARDI-based tractography.