Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Obesity

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...

Drug Dosing: Obese Patients

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...

Binge Eating Disorders

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...

Confounding in Epidemiological Studies

Confounding in Epidemiological Studies

Confounding in statistical epidemiology represents a pivotal challenge, referring to the distortion in the perceived relationship between an exposure and an outcome due to the presence of a third variable, known as a confounder. This variable is associated with both the exposure and the outcome but is not a direct link in their causal chain. Its presence can lead to erroneous interpretations of the exposure's effect, either exaggerating or underestimating the true association. This phenomenon...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Vagina-sparing metoidioplasty: technique and outcomes.

The journal of sexual medicine·2026

Same author

Exploring Perceptions of HPV Risks and Motivations to Vaccination in MSM at a Community-Based HIV Clinic.

AIDS and behavior·2025

Same author

Restoration of branched chain amino acid catabolism improves kidney function in preclinical cardiovascular-kidney-metabolic syndrome models.

Kidney international·2025

Same author

Pros and Cons of Physician Aid in Dying.

The Yale journal of biology and medicine·2019

Same author

Comparative immunogenicity and efficacy of thermostable (lyophilized) and liquid formulation of anthrax vaccine candidate AV7909.

Vaccine·2019

Same author

Aging: Drawing a Map for the Future.

The Hastings Center report·2018

Search research articles

Related Experiment Video

Updated: May 15, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Obesity: chasing an elusive epidemic.

Daniel Callahan

The Hastings Center Report

|December 21, 2012

Summary

Combating widespread obesity in America requires a radical cultural shift, as current lifestyles are deeply ingrained. A more aggressive and simultaneous approach to lifestyle changes is essential for success.

Area of Science:

Public Health
Cultural Studies
Behavioral Science

Background:

Obesity in America represents a significant public health crisis.
The pervasive nature of obesity is deeply intertwined with American culture and lifestyle.
Existing strategies to combat obesity have proven insufficient due to the complexity of cultural factors.

Purpose of the Study:

To highlight the cultural entrenchment of obesity in the United States.
To argue for the necessity of a more aggressive, multifaceted strategy to address the obesity epidemic.
To underscore the challenges posed by deeply ingrained cultural norms in public health interventions.

Main Methods:

This study is primarily conceptual, analyzing the cultural and societal factors contributing to obesity.

More Related Videos

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

An Acupoint Catgut-embedding Therapy for Treating Obesity

An Acupoint Catgut-embedding Therapy for Treating Obesity

Published on: April 4, 2025

Related Experiment Videos

Last Updated: May 15, 2026

Multidisciplinary Approach to Obesity Management: A Case Report

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats

Published on: April 28, 2023

An Acupoint Catgut-embedding Therapy for Treating Obesity

An Acupoint Catgut-embedding Therapy for Treating Obesity

Published on: April 4, 2025

It synthesizes existing research on public health, cultural norms, and behavioral science.

The approach involves a critical examination of the interconnectedness of lifestyle and cultural practices.

Main Results:

The widespread prevalence of obesity is a direct consequence of deeply embedded cultural practices and societal norms.
Individual lifestyle changes are insufficient without simultaneous, large-scale cultural and environmental modifications.
The cultural integration of unhealthy habits presents a formidable barrier to effective obesity control.

Conclusions:

Overcoming the American obesity epidemic necessitates a fundamental reevaluation and transformation of cultural norms and daily living.
A 'business-as-usual' approach is inadequate; a more 'edgy' and comprehensive strategy is required.
Simultaneous, widespread societal changes are crucial for any chance of effectively combating obesity.