Quantitation of abdominal aortic wall dynamics in man by gradient echo NMR imaging

To determine the magnitude of the pulsatile (P), translational (T), and composite (C) aortic wall motion and to predict its effect on endothelial edge definition in vascular NMR imaging, 10 healthy volunteers, mean age 42.5 +/- 13 years, were studied. In each subject a series of transverse high-resolution (0.6 X 0.6 mm; TR = 40 ms) gradient echo images spanning the cardiac cycle were generated and the aortic wall motion dynamics were analyzed. The group data expressed as a mean +/- SD in millimeters, P = 0.87 +/- 0.34 (mm), T = 2.71 +/- 1.07, and C = 3.39 +/- 1.081, indicate that a significant displacement of the endothelial aortic edge (up to 5.6 pixels in high-resolution imaging) occurs during the cardiac cycle in normotensive healthy volunteers. The displacement of this magnitude suggests that cardiac cycle synchronized aortic NMR imaging should be used to improve endothelial edge definition.