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NMR spectral analysis of kinetic data using natural lineshapes
F W Heineman1, J Eng, B A Berkowitz
1Laboratory of Cardiac Energetics, National Heart Blood and Lung Institute, Bethesda, Maryland 20892.
Magnetic Resonance in Medicine
|March 1, 1990
Abstract:
An automated rapid data analysis scheme for NMR spectroscopy time course studies is presented. This method uses a high signal-to-noise reference spectrum collected at the beginning of a time course as a lineshape model to analyze subsequent low signal-to-noise data collected with higher time resolution. The method is fast (approximately 1 s to evaluate two peaks in a 2K spectrum) and easily implemented on NMR spectrometer computers. An application of this method to spectroscopic studies on the heart is provided.