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Primed Mycobacterial Uveitis (PMU) as a Model for Post-Infectious Uveitis
Published on: December 17, 2021
New infectious etiologies for posterior uveitis
Moncef Khairallah1, Rim Kahloun, Salim Ben Yahia
1Department of Ophthalmology, Fattouma Bourguiba University Hospital, Faculty of Medicine, University of Monastir, Monastir, Tunisia. moncef.khairallah@rns.tn
Ophthalmic Research
|December 22, 2012
Summary
Emergent arthropod-borne diseases can cause serious eye problems like uveitis and retinitis. Prevention and supportive care are key, as specific treatments and vaccines are limited.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Public Health
Background:
- Arthropod vector-borne diseases are a growing global health concern, causing significant illness and mortality.
- Viral and bacterial agents like West Nile virus, Dengue fever, Chikungunya, Rift Valley fever, and rickettsioses are increasingly linked to ocular complications.
Purpose of the Study:
- To review the spectrum of ocular manifestations associated with emergent and resurgent arthropod vector-borne diseases.
- To discuss diagnostic approaches, clinical outcomes, and current management strategies for these infections.
Main Methods:
- Review of literature on arthropod vector-borne diseases and their ocular manifestations.
- Analysis of diagnostic criteria, including epidemiological data, clinical signs, and serological confirmation.
- Summary of treatment and prevention strategies for arboviral and rickettsial diseases.
Main Results:
- Ocular involvement includes anterior uveitis, retinitis, chorioretinitis, retinal vasculitis, and optic nerve issues.
- Diagnosis relies on clinical presentation, history, and specific antibody detection in serum.
- While often self-limited, ocular complications can lead to lasting visual impairment.
Conclusions:
- Effective prevention through mosquito control and personal protection is crucial.
- Current treatments for arboviral diseases are primarily supportive; specific vaccines are under development.
- Doxycycline is the recommended treatment for rickettsial diseases.
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