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Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation01:21

Peripheral Arterial Disease II: Clinical Manifestations and Diagnostic Evaluation

Clinical manifestationsPeripheral Arterial Disease (PAD) manifests through a range of symptoms, from the characteristic intermittent claudication to atypical presentations and severe complications in advanced stages. Intermittent claudication, a hallmark symptom of PAD, presents as exercise-induced muscle pain that typically resolves within minutes of rest. This pain is reproducible and stems from inadequate blood flow, leading to the accumulation of lactic acid produced during anaerobic...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Peripheral Artery Disease I: Introduction01:30

Peripheral Artery Disease I: Introduction

Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...

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Related Experiment Video

Updated: May 15, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
06:26

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Published on: March 28, 2025

Type A aortic dissection presenting with isolated paraplegia.

Athanasios Tsiouris1, Jeffrey A Morgan, Gaetano Paone

  • 1Department of Surgery, Division of Cardiothoracic Surgery, Henry Ford Hospital, Heart and Vascular Institute, Detroit, MI 48202, USA.

The Heart Surgery Forum
|December 25, 2012
PubMed
Summary
This summary is machine-generated.

Acute type A aortic dissection can cause sudden paralysis by affecting the artery of Adamkiewicz. This rare presentation highlights the importance of considering aortic dissection in the differential diagnosis of acute paraplegia.

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Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
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Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

Published on: March 3, 2014

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Last Updated: May 15, 2026

Novel and Innovative Hybrid Technique for Type A Aortic Dissection
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Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion
05:59

Reproducable Paraplegia by Thoracic Aortic Occlusion in a Murine Model of Spinal Cord Ischemia-reperfusion

Published on: March 3, 2014

Area of Science:

  • Cardiovascular Surgery
  • Neurology
  • Vascular Medicine

Background:

  • Acute type A aortic dissection (ATAAD) is a life-threatening condition.
  • Typical symptoms include severe chest or back pain.
  • Neurological complications are known but varied.

Observation:

  • A patient presented with acute, painless paraplegia.
  • The paraplegia was attributed to malperfusion of the artery of Adamkiewicz.
  • This is an atypical presentation for ATAAD.

Findings:

  • The patient's paraplegia resulted from compromised blood flow to the spinal cord.
  • The underlying cause was identified as an acute type A aortic dissection.
  • This case demonstrates a rare neurological manifestation of ATAAD.

Implications:

  • Thoracic aortic dissection should be considered in the differential diagnosis of acute paraplegia, even without typical pain.
  • Early recognition of this uncommon presentation is crucial for timely intervention and improved outcomes.
  • Highlights the complex interplay between aortic pathology and spinal cord perfusion.