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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
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Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

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Related Experiment Video

Updated: May 15, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

Treatment options for diffuse diabetic macular edema.

Francesco Bandello1, Pierluigi Iacono, Maurizio Battaglia Parodi

  • 1Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Milan, Italy. bandello.francesco@hsr.it

European Journal of Ophthalmology
|December 25, 2012
PubMed
Summary

Diffuse diabetic macular edema (DDME) management involves various treatments like laser, steroids, anti-VEGF injections, and surgery. New intravitreal therapies offer promising options for this condition.

Related Experiment Videos

Last Updated: May 15, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
10:24

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

Area of Science:

  • Ophthalmology
  • Diabetology

Background:

  • Diabetic macular edema (DME) is a leading cause of vision loss in diabetic patients.
  • Diffuse diabetic macular edema (DDME) presents unique challenges in management.

Purpose of the Study:

  • To provide a comprehensive overview of current management strategies for diffuse diabetic macular edema (DDME).

Main Methods:

  • Literature review and discussion of existing research on DDME treatments.

Main Results:

  • Current management options for DDME include focal/grid laser photocoagulation.
  • Intravitreal or periocular corticosteroids, and intravitreal anti-vascular endothelial growth factor (VEGF) agents are utilized.
  • Surgical intervention, such as vitrectomy with or without internal limiting membrane peeling, is also an option.

Conclusions:

  • While no definitive randomized clinical trials specifically target DDME, emerging therapies show promise.
  • Intravitreal corticosteroid and anti-VEGF injections represent significant advancements in DDME management.