Treatment options for diffuse diabetic macular edema
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Updated: May 15, 2026

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report
Published on: February 12, 2018
Francesco Bandello1, Pierluigi Iacono, Maurizio Battaglia Parodi
1Department of Ophthalmology, University Vita-Salute, Scientific Institute San Raffaele, Milan, Italy. bandello.francesco@hsr.it
Purpose:
To describe the current management of diffuse diabetic macular edema (DDME).
Methods:
Review and discussion of the literature regarding DDME.
Results:
Diffuse diabetic macular edema is a condition that can be managed by means of several treatment options, including focal/grid laser photocoagulation, intravitreal or periocular corticosteroids, intravitreal anti-vascular endothelial growth factor (VEGF), and vitrectomy with or without internal limiting membrane peeling.
Conclusions:
Even though there is no randomized clinical trial specifically designed to assess the best treatment approach for DDME, new therapeutic approaches based on intravitreal injections of corticosteroid and anti-VEGF molecules offer new hope for its management.
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