Related Experiment Video
Updated: May 15, 2026
08:46
A Real-time Potency Assay for Chimeric Antigen Receptor T Cells Targeting Solid and Hematological Cancer Cells
Published on: November 12, 2019
Modulating CD27 signaling to treat cancer
Carsten Riether1, Christian Schürch, Adrian F Ochsenbein
1Tumor Immunology; Department of Clinical Research; University of Bern; Bern, Switzerland.
Oncoimmunology
|December 25, 2012
Abstract:
CD27 signaling can either improve T-cell function or lead to T-cell dysfunction, depending on the duration and conditions of receptor ligation. Recent studies have shown that modulating the CD70-CD27 interaction is an attractive strategy to treat solid tumors and also to directly target leukemia stem cells.
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