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Updated: May 15, 2026

Intramucosal Inoculation of Squamous Cell Carcinoma Cells in Mice for Tumor Immune Profiling and Treatment Response Assessment
Published on: April 22, 2019
Radiation and immunotherapy: Renewed allies in the war on cancer
Steven K Seung1, Brendan Curti, Marka Crittenden
1Earle A. Chiles Research Institute; Portland, OR USA ; The Oregon Clinic; Portland, OR, USA ; Providence Cancer Center; Portland, OR USA.
Abstract:
Anticancer immunotherapy holds great promises, as long-term responses to interleukin-2 have been observed in metastatic melanoma and renal cell carcinoma patients. However, improving the relative low rates of such responses has constituted a great challenge. In our experience, high-dose radiation combined with interleukin-2 provided encouraging results that are worth exploring further.
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