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Experimental Infection of Mice with the Parasitic Nematode Strongyloides ratti
Published on: January 17, 2025
Fatal Strongyloides stercoralis infection in a patient with chronic inflammatory demyelinating polyneuropathy
Jayantee Kalita1, Sanjeev K Bhoi, Usha Kant Misra
1Department of Neurology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Abstract:
A 50-year-old villager with chronic inflammatory demyelinating polyradiculoneuropathy developed pain abdomen, diarrhea, and vomiting after 8 weeks of prednisolone (40 mg/day) therapy. After 10 weeks, he developed abdominal distension, leucocytosis, thrombocytopenia, liver dysfunction, coagulopathy, and respiratory failure. Stool examination showed larvae of Strongyloides stercoralis. He died in spite of antibiotics, metronidazole, ivermectin, vasopressor, and artificial ventilation. The patients on corticosteroid therapy are at risk of fatal septicemia due to Strongyloides stercoralis hyperinfection.
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