Related Experiment Video
Updated: May 15, 2026
07:56
Transient Middle Cerebral Artery Occlusion Model of Neonatal Stroke in P10 Rats
Published on: April 21, 2017
Ruptured intracranial aneurysms in pediatric polyarteritis nodosa: case report
Keisuke Toyoda1, Keisuke Tsutsumi, Tomohito Hirao
1Department of Neurosurgery, National Hospital Organization Nagasaki Medical Center, Ohmura, Nagasaki.
Neurologia Medico-Chirurgica
|December 28, 2012
Summary
Polyarteritis nodosa (PAN) can cause rare intracranial aneurysms in children, leading to strokes. Early intervention and monitoring are crucial for managing these vascular complications.
Area of Science:
- Neurology
- Rheumatology
- Pediatrics
Background:
- Polyarteritis nodosa (PAN) is a systemic necrotizing vasculitis affecting small to medium arteries.
- Intracranial aneurysms are uncommon manifestations of PAN, particularly in pediatric cases.
Observation:
- A pediatric patient with PAN experienced sequential hemorrhagic strokes.
- These strokes resulted from a ruptured superior cerebellar artery aneurysm and a newly formed frontoorbital artery aneurysm.
Findings:
- The study highlights the occurrence of both ruptured and de novo intracranial aneurysms in a child with PAN.
- This case underscores the potential for serious cerebrovascular events in pediatric PAN.
Implications:
- Patients with PAN and intracranial aneurysms warrant consideration for interventional treatment, irrespective of aneurysm size.
- Vigilant surveillance is essential for detecting new aneurysms in individuals with a history of PAN.
Related Concept Videos
01:27Acute Pyelonephritis I: Introduction
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such as Proteus,...
01:30Aneurysm I: Introduction
An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
01:26Aneurysm III: Interprofessional Care
Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
01:21Aneurysm II: Clinical Manifestations and Diagnostic Studies
Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...