Cutaneous Rosai-Dorfman disease

Area of Science:

• Dermatology
• Pathology
• Oncology

Background:

• Rosai-Dorfman disease (RDD) is a rare histiocytic proliferative disorder.
• Typically, RDD involves lymphadenopathy, but extranodal and cutaneous forms exist.
• Cutaneous Rosai-Dorfman disease (CRDD) is a rare variant confined to the skin.

Observation:

• This case report describes a patient with CRDD localized to the trunk.
• The presentation involved skin lesions consistent with CRDD.
• No lymphadenopathy was reported in this specific case.

Findings:

• The patient's CRDD was strictly limited to the skin of the trunk.
• Histopathological examination confirmed the diagnosis of CRDD.
• Literature review on CRDD is provided for context.

Implications:

• This case expands the understanding of CRDD presentation and localization.
• Highlights the importance of considering CRDD in the differential diagnosis of trunk skin lesions.
• Contributes to the literature on rare extranodal variants of Rosai-Dorfman disease.