[Atypical ventricular tachycardia and atrioventricular blockade]
1II. Katedra internej medicíny Lekárskej fakulty Univerzity Pavia Jozefa Safárika, Kosice.
Insights
Atypical ventricular tachycardia in patients with advanced atrioventricular block is rare but linked to low potassium and prolonged QT intervals. Drug correction and discontinuation are crucial, as pacing alone may not prevent this tachycardia.
Area of Science:
- Cardiology
- Electrophysiology
- Internal Medicine
Context:
- Atypical ventricular tachycardia (AVT) is a rare complication in patients with advanced atrioventricular block (AVB).
- This condition affects approximately 1% of patients with AVB.
- Identifying risk factors and effective management strategies is crucial for patient outcomes.
Purpose:
- To analyze the clinical and electrocardiographic features of five patients experiencing AVT with advanced AVB.
- To investigate the role of serum potassium levels, QT interval, and specific medications in the development of AVT.
- To evaluate the efficacy of interventions such as drug discontinuation and permanent pacing.
Summary:
- The study presents five cases of AVT in patients with advanced AVB, noting common findings of hypokalemia and prolonged QT intervals.
- Two cases were associated with drug use (Furosemide, Thioridazine), and tachycardia persisted despite permanent pacing.
- Correction of electrolyte imbalances and drug withdrawal were decisive in managing the tachycardia, suggesting prolonged bradycardia may precipitate AVT.
Impact:
- Highlights the importance of monitoring electrolytes and QT intervals in patients with AVB.
- Underscores the potential role of certain medications in triggering AVT.
- Emphasizes that comprehensive management, including drug review and metabolic correction, is essential, potentially offering alternatives or adjuncts to pacing in preventing AVT.
Abstract:
The authors submit a clinical and electrocardiographic analysis of five patients with atypical ventricular tachycardia with atrioventricular block of an advanced degree. The incidence is relatively rare--cca 1% patients with atrioventricular block are threatened by this type of tachycardia. In these patients there are always reduced serum potassium levels and a longer QT interval, as compared with patients without tachycardia. In two instances there was an association with the use of drugs (Furosemide and Thioridazine) and these patients developed tachycardia even during permanent pacing. Correction of the internal environment and discontinuation of drugs proved therefore decisive, as permanent pacing alone did not always suffice to prevent tachycardia. Without medication atypical ventricular tachycardia develops, in the author's opinion, most probably when bradycardia has persisted for a prolonged period.
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