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Identification and Quantification of Deranged Metabolites in Critically Ill Patients Using NMR-Based Metabolomics
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Published on: November 29, 2024

Trace elements in critically ill patients.

Joseph I Boullata1

  • 1University of Pennsylvania School of Nursing, Philadelphia, Pennsylvania 19104, USA. boullata@nursing.upenn.edu

Journal of Infusion Nursing : the Official Publication of the Infusion Nurses Society
|December 29, 2012
PubMed
Summary
This summary is machine-generated.

Trace elements are vital nutrients for critically ill patients, administered via enteral and parenteral nutrition. Intravenous trace element infusions can improve biomarkers and patient outcomes when clinically indicated.

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Area of Science:

  • Clinical Nutrition
  • Critical Care Medicine
  • Trace Element Metabolism

Background:

  • Trace elements are essential micronutrients for critically ill patients.
  • They are commonly supplied through enteral nutrition (EN) and parenteral nutrition (PN).
  • Specific trace elements may be needed intravenously based on clinical assessment.

Purpose of the Study:

  • To highlight the importance of trace elements in critically ill patients.
  • To discuss the role of intravenous trace element administration.
  • To emphasize individualized regimens based on patient needs and evidence.

Main Methods:

  • Review of current practices in trace element supplementation for critically ill patients.
  • Identification of key trace elements available for intravenous use (chromium, copper, manganese, selenium, zinc).
  • Emphasis on clinical assessment for determining the need for individual trace element infusions.

Main Results:

  • Intravenous administration of specific trace elements is feasible and indicated in certain cases.
  • Improved measured biomarkers are associated with intravenous trace element therapy.
  • Potential for improved patient outcomes with appropriate trace element management.

Conclusions:

  • Trace elements are crucial for critically ill patients.
  • Intravenous trace element supplementation can be a valuable therapeutic option.
  • Personalized administration based on clinical evaluation and evidence is recommended.