[Delayed hypersensitivity to staphylococcal antigens in patients with staphylodermas]

Basing on analysis of delayed skin reactions to staphylococcal vaccine, on findings of pathohistologic examinations of the skin in foci of delayed type hypersensitivity, on the parameters of the lymphocyte, monocyte, and neutrophil migration into these foci, as well as on the clinical parameters and findings of the spontaneous rosette-formation, lymphocyte blastogenesis, leukocyte migration inhibition tests with the specific antigen, and DNCB skin test, carried out in 312 patients with staphylodermas, the author comes to a conclusion on the protective role of delayed type hypersensitivity to Staphylococcus, reveals some mechanisms of the formation of skin response reactions, and points to some factors responsible for inhibition of these reactions.