Related Experiment Video

Updated: May 15, 2026

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
09:11

Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability

Published on: February 23, 2016

Carotid disease in diabetic patients undergoing coronary artery bypass grafting

Muhammad Shahid1, Abdul Rehman Abid, Muhammad Ashraf Dar

  • 1Punjab Institute of Cardiology, Lahore, Pakistan. drshahid68@hotmail.com

Journal of Ayub Medical College, Abbottabad : JAMC
|January 1, 2013
PubMed

Insights

Diabetic patients undergoing coronary artery bypass grafting have a higher prevalence of significant carotid artery disease and diffuse coronary artery disease compared to non-diabetics. This highlights the importance of assessing carotid health in diabetic patients before surgery.

Area of Science:

  • Cardiovascular Surgery
  • Diabetology
  • Vascular Medicine

Background:

  • Diabetes mellitus is a significant risk factor for cardiovascular disease.
  • Coronary artery bypass grafting (CABG) is a common procedure for severe coronary artery disease.
  • Carotid artery disease can increase the risk of stroke during or after CABG.

Purpose of the Study:

  • To compare the severity of carotid artery disease in diabetic versus non-diabetic patients undergoing CABG.
  • To investigate the association between diabetes and coronary artery disease patterns in patients undergoing CABG.

Main Methods:

  • A prospective study of 379 patients undergoing elective CABG from January to June 2008.
  • Preoperative duplex scanning to assess carotid stenoses.
  • Patients divided into diabetic (n=156) and non-diabetic (n=223) groups.

Main Results:

  • Diabetic patients showed a higher incidence of left main stem stenosis (37.8% vs 20.2%, p<0.0001).
  • Significant carotid artery stenosis was more prevalent in diabetics (19.2% vs 9%, p<0.004).
  • >70% carotid stenosis was also more frequent in diabetics (8.3% vs 3.1%, p<0.025).

Conclusions:

  • Diabetes mellitus is associated with more diffuse coronary artery disease.
  • Diabetic patients undergoing CABG have a significantly higher prevalence of significant carotid artery disease.
  • Preoperative screening for carotid artery disease is crucial in diabetic patients scheduled for CABG.
Abstract

More Related Videos

A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium11:00

A Model of Disturbed Flow-Induced Atherosclerosis in Mouse Carotid Artery by Partial Ligation and a Simple Method of RNA Isolation from Carotid Endothelium

Published on: June 22, 2010

Related Concept Videos

Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Complications of Diabetes Mellitus01:22

Complications of Diabetes Mellitus

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insulin deficiency, resistance, or both. Prolonged hyperglycemia disrupts metabolic homeostasis and leads to acute and chronic complications.Acute ComplicationsAcute complications result from sudden metabolic imbalance.Diabetic ketoacidosis (DKA) mainly appears in type 1 diabetes but may also develop in type 2 diabetes, particularly under extreme stress. It arises from severe insulin deficiency,...
Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Atherosclerosis II: Clinical Manifestations and Diagnostic Tests01:27

Atherosclerosis II: Clinical Manifestations and Diagnostic Tests

Atherosclerosis is a progressive disorder that leads to the thickening and narrowing of arterial walls due to plaque buildup. This condition can cause various symptoms depending on the arteries affected:Coronary Artery Disease (CAD): This condition affects the coronary arteries and may lead to chest pain (angina), shortness of breath (dyspnea), heart attacks, and other heart disease symptoms.Cerebrovascular Disease: This affects blood flow to the brain, causing transient ischemic attacks (TIAs)...