Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pleiotropy01:33

Pleiotropy

Pleiotropy is the phenomenon in which a single gene impacts multiple, seemingly unrelated phenotypic traits. For example, defects in the SOX10 gene cause Waardenburg Syndrome Type 4, or WS4, which can cause defects in pigmentation, hearing impairments, and an absence of intestinal contractions necessary for elimination. This diversity of phenotypes results from the expression pattern of SOX10 in early embryonic and fetal development. SOX10 is found in neural crest cells that form melanocytes,...
Genetic Lingo01:11

Genetic Lingo

Overview
Sex Linked Disorders01:43

Sex Linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Sex-linked Disorders01:43

Sex-linked Disorders

Like autosomes, sex chromosomes contain a variety of genes necessary for normal body function. When a mutation in one of these genes results in biological deficits, the disorder is considered sex-linked.
Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Dissociative Identity Disorder01:30

Dissociative Identity Disorder

Dissociative Identity Disorder (DID), previously termed multiple personality disorder, is a complex psychological condition characterized by the presence of two or more distinct identities or personality states. Each identity exhibits unique patterns of behavior, voice, and mannerisms and may possess separate memories and emotional responses. The alternating control between identities can result in memory gaps and challenges in recalling daily activities, often exacerbating the individual's...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The New Science of Practical Wisdom.

Perspectives in biology and medicine·2019
Same author

Race, then and now: 1918 revisited.

American journal of physical anthropology·2018
Same author

A single lineage in early Pleistocene Homo: size variation continuity in early Pleistocene Homo crania from East Africa and Georgia.

Evolution; international journal of organic evolution·2013
Same author

The evolution of grandparents.

Scientific American·2011
Same author

How Neandertals inform human variation.

American journal of physical anthropology·2009
Same author

1918: Three perspectives on race and human variation.

American journal of physical anthropology·2009

Related Experiment Video

Updated: May 15, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

The Dubois syndrome.

Rachel Caspari1, Milford H Wolpoff

  • 1Department Sociology, Anthropology, and Social Work Central Michigan University, Mount Pleasant, MI 48859, USA.

History and Philosophy of the Life Sciences
|January 1, 2013
PubMed
Summary

The Dubois syndrome describes how scientists may resist falsifying hypotheses, even when evidence suggests it. This phenomenon, exemplified by Eugène Dubois, highlights challenges in accepting evolutionary theory shifts.

Area of Science:

  • Paleoanthropology
  • Evolutionary Biology
  • Philosophy of Science

Background:

  • The scientific method emphasizes falsification of hypotheses.
  • Eugène Dubois's interpretation of Pithecanthropus erectus fossils faced resistance.
  • Resistance to refutation can hinder scientific progress.

Discussion:

  • The "Dubois syndrome" illustrates the psychological and theoretical inertia in science.
  • Dubois's changing interpretations were rational within his evolutionary framework.
  • This syndrome is prevalent in fields with limited data, like paleoanthropology.

Key Insights:

  • Scientific adherence to broad theories can lead to resistance against falsifying evidence.
  • Apparent "capriciousness" in scientific interpretation may stem from a commitment to existing paradigms.

More Related Videos

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder
08:30

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

Related Experiment Videos

Last Updated: May 15, 2026

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
06:41

In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila

Published on: August 20, 2019

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder
08:30

Paradigms for Behavioral Assessment in Drosophila Model of Autism Spectrum Disorder

Published on: September 6, 2024

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans
08:29

Symmetric Bihemispheric Postmortem Brain Cutting to Study Healthy and Pathological Brain Conditions in Humans

Published on: December 18, 2016

  • Understanding the Dubois syndrome is crucial for evaluating scientific progress.
  • Outlook:

    • Recognizing the Dubois syndrome can foster more objective data interpretation.
    • Encouraging open-mindedness towards evolving scientific understanding is vital.
    • Further research into cognitive biases in science is warranted.