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Updated: May 15, 2026

In vitro Assessment of Myocardial Protection following Hypothermia-Preconditioning in a Human Cardiac Myocytes Model
Published on: October 27, 2020
Left ventricular systolic dysfunction in a patient with accidental hypothermia: a case report
Takanao Mine1, Ikuo Sato, Hideyuki Kishima
1Department of Internal Medicine, Cardiovascular Division, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Japan. mine@hyo-med.ac.jp.
Introduction:
Hypothermia is a relatively rare condition, and the effects of unintentional hypothermia on the heart are not known.
Case Presentation:
This report describes the case of an 88-year-old Japanese man found in a coma and presenting with heart failure associated with hypothermia. He experienced sinus arrest, junctional rhythm and left ventricular systolic dysfunction with prolonged ejection time. With rewarming and treatment of his heart failure, he completely recovered over a period of two weeks.
Conclusion:
Prolonged ejection time might be a characteristic finding in hypothermia.
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