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Related Concept Videos

Radiological Investigation I: X-ray and CT01:30

Radiological Investigation I: X-ray and CT

Radiological investigations, including X-rays and computed tomography (CT) scans, are critical for diagnosing and evaluating various medical conditions. These imaging techniques provide valuable insights into the body's internal structures, aiding in the detection of abnormalities, assessment of disease progression, and development of treatment strategies. This article delves into two primary radiological investigations, chest X-rays and CT scans, outlining their purpose, procedures, and the...
Radiological Investigation III: Pulmonary Angiogram and PET Scan01:13

Radiological Investigation III: Pulmonary Angiogram and PET Scan

Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Detailed Structure and Function of Lymph Nodes01:23

Detailed Structure and Function of Lymph Nodes

Lymph nodes are bean-shaped structures that cluster along the lymphatic vessels in the inguinal, axillary, and cervical regions. Each node is divided into compartments by a capsule that extends trabeculae inward.
From a histological perspective, lymph nodes can be split into two main areas: the superficial cortex and the deep medulla. The outer cortex is populated by dendritic cells, macrophages, and B lymphocytes, which are densely packed into follicles. When these B-lymphocytes are presented...
Primary Lymphoid Organs01:16

Primary Lymphoid Organs

Primary lymphoid organs are pivotal in the formation, development, and maturation of lymphocytes, the white blood cells that serve as the backbone of our immune system. This crucial function underscores their fundamental role in maintaining our overall health and immunity. The two primary lymphoid organs of prime importance are the red bone marrow and the thymus.
The red bone marrow is a soft, spongy tissue nestled in the interior of long bones such as the humerus and femur. It is the site...
Lymphoid Cells and Tissues01:18

Lymphoid Cells and Tissues

Lymphoid cells and tissues are integral to the immune system, which is crucial in maintaining our body's defense against harmful pathogens. They form the building blocks of lymphoid organs, which include the spleen, thymus, and lymph nodes.
Lymphoid cells consist of various types of immune system cells. These include B and T lymphocytes, which are responsible for producing antibodies and killing infected cells, respectively. Dendritic cells act as messengers between the innate and adaptive...

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Updated: May 15, 2026

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
07:52

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Published on: January 9, 2019

Lymphomas: Basic points that radiologists should know.

E Frampas1

  • 1Central Radiology and Medical Imaging Department, Hôtel-Dieu, CHU de Nantes, 1, place Alexis-Ricordeau, 44093 Nantes cedex 1, France.

Diagnostic and Interventional Imaging
|January 1, 2013
PubMed
Summary
This summary is machine-generated.

Diagnosing lymphomas, which affect the lymphoid system, can be challenging due to varied presentations and rarity. Recognizing predisposing factors and specific radiological signs is crucial for accurate diagnosis and timely biopsy.

Keywords:
BiopsyCT scansLymph nodesLymphomaOncology

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Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
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Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
07:52

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma

Published on: January 9, 2019

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections
06:09

Quantification of Tumor Cell Adhesion in Lymph Node Cryosections

Published on: February 9, 2020

Area of Science:

  • Oncology
  • Radiology
  • Pathology

Background:

  • Lymphomas are cancers of the lymphoid system with diverse clinical and imaging presentations.
  • The varied aggressiveness and rarity of lymphomas can complicate diagnosis, especially when compared to more common diseases.
  • Imaging plays a key role, but the polymorphic nature of lymphoma expression requires careful interpretation.

Purpose of the Study:

  • To highlight the diagnostic challenges posed by lymphomas on medical imaging.
  • To emphasize the importance of recognizing predisposing factors and specific radiological signs of lymphoma.
  • To underscore the necessity of integrating imaging findings with biopsy for definitive diagnosis.

Main Methods:

  • Review of imaging characteristics of various lymphoma types across different organs.
  • Analysis of predisposing factors associated with lymphoma development.
  • Correlation of radiological findings with histopathological confirmation.

Main Results:

  • Lymphoma presentation on imaging is highly variable depending on the affected organ and lymphoma subtype.
  • Certain radiological patterns and predisposing factors can suggest a lymphoma diagnosis.
  • Imaging findings alone are often insufficient for definitive diagnosis, necessitating biopsy.

Conclusions:

  • Accurate diagnosis of lymphomas requires a comprehensive approach combining clinical information, imaging interpretation, and histopathological analysis.
  • Radiologists and clinicians should be aware of the diverse imaging manifestations of lymphoma.
  • Prompt biopsy guided by imaging suspicion is essential for confirming lymphoma and guiding treatment.