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Related Experiment Video

Updated: May 15, 2026

Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography

Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography

Published on: December 27, 2024

Vitamin D3: an ever green molecule.

Michele Di Rosa¹, Lucia Malaguarnera, Anna Nicolosi

¹Department of Biomedical Sciences, University of Catania, Catania, Italy. miky.dirosa@hotmail.it

Frontiers in Bioscience (Scholar Edition)

|January 2, 2013

Summary

Vitamin D3 is crucial for vertebrate health, synthesized via UVB exposure and metabolized in the liver and kidneys. This review explores its role in diseases and immune cell function.

Related Experiment Videos

Last Updated: May 15, 2026

Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography

Quantitative Analysis of Dietary Vitamin A Metabolites in Murine Ocular and Non-Ocular Tissues Using High-Performance Liquid Chromatography

Published on: December 27, 2024

Area of Science:

Endocrinology
Immunology
Dermatology

Background:

Vitamin D3 is essential for vertebrate homeostasis.
It is synthesized in the skin via UVB exposure from 7-dehydrocholesterol.
Further metabolism occurs in the liver and kidneys to form the active calcitriol.

Purpose of the Study:

To review vitamin D3 metabolism.
To discuss the association between vitamin D3 levels and various pathological conditions.
To explore the link between vitamin D3 and immune cells.

Main Methods:

Literature review of vitamin D3 metabolism and function.
Analysis of evidence linking vitamin D3 to diseases like osteoporosis, cancer, and immune disorders.
Examination of vitamin D3's interaction with immune cells.

Main Results:

Vitamin D3 synthesis is dependent on UVB radiation and specific environmental factors.
Altered vitamin D3 levels are implicated in numerous diseases.
Vitamin D3 plays a significant role in immune system regulation.

Conclusions:

Vitamin D3 is a vital regulator of homeostasis with broad physiological effects.
Understanding vitamin D3 metabolism and its role in disease is critical for public health.
Further research into the vitamin D3-immune cell axis may reveal new therapeutic strategies.