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Updated: May 15, 2026
10:49
Laboratory-determined Phosphorus Flux from Lake Sediments as a Measure of Internal Phosphorus Loading
Published on: March 6, 2014
Contributions to total phosphorus intake: all sources considered
1Office of Applied Research and Safety Assessment, Center for Food Safety and Applied Nutrition, U.S. Food and Drug Administration, Department of Health and Human Services, Laurel, Maryland, USA.
Seminars in Dialysis
|January 3, 2013
Summary
High phosphorus intake worsens health in chronic kidney disease (CKD) patients. Current tools underestimate dietary phosphorus, missing hidden sources in processed foods and medications, hindering effective management for CKD and dialysis patients.
Area of Science:
- Nephrology
- Nutritional Science
- Public Health
Background:
- Elevated serum phosphorus is a significant risk factor for adverse health outcomes and mortality in chronic kidney disease (CKD) patients, both pre-dialysis and on dialysis.
- Accurate assessment of dietary phosphorus intake is crucial for managing CKD, but current methods often underestimate total intake.
Purpose of the Study:
- To review and identify underappreciated sources of dietary phosphorus in the American food supply.
- To highlight the limitations of existing nutrient databases and software in accounting for all phosphorus contributors.
- To inform future interventions for better dietary phosphorus control in CKD and dialysis patients.
Main Methods:
- Literature review focusing on dietary phosphorus sources.
- Analysis of nutrient content databases and software limitations.
- Exploration of phosphorus in processed foods, supplements, and medications.
Main Results:
- Standard dietary assessment tools systematically underestimate phosphorus intake.
- Significant phosphorus contributions from food additives, supplements, and medications are often overlooked.
- Existing nutrient databases lack comprehensive data on all phosphorus sources.
Conclusions:
- There is a critical need to account for all dietary phosphorus sources, including hidden ones, for accurate patient management.
- Improved methods for assessing total phosphorus intake are essential for effective interventions in CKD and dialysis.
- Addressing underestimated phosphorus intake can improve health outcomes and quality of life for CKD patients.
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