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Development and Evaluation of 3D-Printed Cardiovascular Phantoms for Interventional Planning and Training
09:57

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Published on: January 18, 2021

An alternative method to create highly transparent hollow models for flow visualization.

Martin Stoiber1, Thomas Schlöglhofer, Philipp Aigner

  • 1Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna - Austria. martin.stoiber@meduniwien.ac.at

The International Journal of Artificial Organs
|January 3, 2013
PubMed
Summary

This study introduces a new and affordable method for creating transparent hollow models used in flow visualization experiments. Traditional methods rely on intermediate materials that can be toxic, expensive, or harmful to model transparency. The researchers tested chocolate as an alternative material for shaping fluid spaces before casting transparent silicone. They found that chocolate could be easily removed after casting and did not compromise the model's transparency. The final models showed excellent optical quality and geometric accuracy. This method offers a safer and more cost-effective solution for producing transparent models suitable for biomedical and engineering applications.

Keywords:
transparent model castingfluid dynamics visualizationbiomedical modelingalternative molding materials

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Area of Science:

  • Biomedical modeling and visualization
  • Fluid dynamics in cardiovascular systems
  • Materials science for transparent casting

Background:

Creating transparent models to study fluid flow is essential in biomedical and engineering contexts. Traditional methods rely on intermediate materials to shape fluid spaces before casting transparent materials. However, these materials often pose challenges like toxicity, high cost, and interference with model transparency. Prior research has shown that such limitations hinder the creation of high-quality transparent models. This gap motivated the search for safer and more cost-effective alternatives. No prior work had resolved the issue of material penetration affecting transparency. Existing methods also lacked geometric precision in replicating complex anatomical structures. The need for an affordable and non-toxic solution became apparent. This study addresses the limitations of current approaches by proposing a novel method using a familiar and accessible material.

Purpose Of The Study:

The goal of this study was to develop a new method for creating transparent hollow models using a non-toxic and easily removable intermediate material. The researchers aimed to overcome the limitations of existing materials that affect transparency and accuracy. They focused on using chocolate as a fluid-space molding material due to its unique properties. The study sought to evaluate whether chocolate could serve as a viable alternative in this process. The specific problem addressed was the degradation of model transparency caused by intermediate materials. The motivation for this work was to provide a safer and more cost-effective solution for model creation. The researchers also aimed to test the geometric accuracy of the resulting models. Their approach aimed to maintain optical quality while reducing material costs and health risks.

Main Methods:

The researchers began with a three-dimensional CAD model of a human aorta. They used chocolate to create a fluid-space mold based on this geometry. The chocolate mold was then coated and cast in a block of transparent silicone. After the silicone cured, the chocolate was removed using hot water. The team measured the geometric accuracy of the chocolate mold compared to the original CAD model. They assessed the transparency of the final silicone casting using particle tracking methods. The refractive index of the fluid used in testing matched that of the silicone. This allowed them to evaluate how well the fluid boundaries remained invisible. The process was designed to be both cost-effective and safe for users.

Main Results:

The geometric accuracy of the chocolate mold was found to be within 5.7% of the original CAD model. The silicone casting showed no defects and achieved perfect transparency. Particle tracking experiments confirmed that fluid boundaries were invisible when using a matching refractive index fluid. The chocolate mold was successfully removed using hot water without damaging the silicone. The final model maintained excellent optical quality suitable for flow visualization. The process was significantly cheaper than traditional methods. No penetration of the intermediate material into the silicone was observed. The results suggest that chocolate is a viable alternative to current molding materials.

Conclusions:

The authors concluded that chocolate is a suitable material for creating fluid-space molds in transparent model production. The method they describe is both cost-effective and safe to use. Their findings suggest that chocolate can be removed cleanly without affecting model transparency. The geometric accuracy of the chocolate mold was sufficient for biomedical applications. The process does not require toxic or expensive materials. The final silicone casting achieved optical quality suitable for flow studies. The results support the use of chocolate as an alternative to traditional molding materials. The authors propose that this method could be applied to other anatomical structures and engineering models.

Using chocolate as a fluid-space molding material allows for the creation of transparent models with excellent optical quality and geometric accuracy.

Sylgard 184 was selected for its high transparency and compatibility with particle tracking methods used in flow visualization.

The chocolate mold was removed using hot water, which melted the chocolate without damaging the silicone casting.

Matching the refractive index of the fluid to the silicone ensured fluid boundaries remained invisible during flow visualization.

The chocolate mold had a mean divergence of 5.7% from the original CAD geometry of the aorta.

The authors propose that the chocolate-based method is a cheap and effective way to create transparent models with excellent optical quality.