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Related Concept Videos

MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns (non-coding regions of a gene) or intergenic regions (stretches of DNA present between genes). Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself, forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...
MicroRNAs01:22

MicroRNAs

MicroRNA (miRNA) are short, regulatory RNA transcribed from introns—non-coding regions of a gene—or intergenic regions—stretches of DNA present between genes. Several processing steps are required to form biologically active, mature miRNA. The initial transcript, called primary miRNA (pri-mRNA), base-pairs with itself forming a stem-loop structure. Within the nucleus, an endonuclease enzyme, called Drosha, shortens the stem-loop structure into hairpin-shaped pre-miRNA. After the pre-miRNA ends...

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Updated: May 15, 2026

MicroRNA In situ Hybridization for Formalin Fixed Kidney Tissues
12:21

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Published on: November 30, 2013

MicroRNAs and lung development.

Naghmeh Khoshgoo1, Ramin Kholdebarin, Barbara Maria Iwasiow

  • 1Department of Surgery, University of Manitoba, Winnipeg, Manitoba, Canada.

Pediatric Pulmonology
|January 3, 2013
PubMed
Summary
This summary is machine-generated.

MicroRNAs (miRNAs), small non-coding RNAs, are crucial for gene regulation and organ development. Emerging research highlights their significant roles in various stages of lung development and organogenesis.

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Last Updated: May 15, 2026

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Area of Science:

  • Molecular Biology
  • Developmental Biology
  • Genetics

Background:

  • MicroRNAs (miRNAs) are small, non-coding RNA molecules with conserved regulatory functions.
  • They play critical roles in gene regulation across diverse organisms.
  • Recent research highlights their importance in organ development, particularly in the lung.

Purpose of the Study:

  • To provide an overview of microRNAs implicated in lung organogenesis.
  • To summarize current understanding of miRNA roles in lung development.

Main Methods:

  • Literature review of studies profiling miRNA expression during lung development.
  • Analysis of research identifying specific miRNAs involved in lung organogenesis.

Main Results:

  • Numerous miRNAs have been identified to play significant roles in both early and late lung development.
  • Expression profiling studies reveal dynamic miRNA patterns throughout lung development stages.

Conclusions:

  • MicroRNAs are key regulators of lung organogenesis.
  • Further research into specific miRNAs will elucidate their precise functions in lung development.