Risk factors for adenomyosis
1Department of Obstetrics and Gynaecology, Chitwan Medical College, Chitwan, Nepal. anjushr2002@yahoo.co.in
Journal of Nepal Health Research Council
|January 3, 2013
Summary
Adenomyosis risk factors include multiparity, prior abortion, and smoking. Irregular cycles and dilatation and curettage also increase adenomyosis risk, highlighting the need for further research.
Area of Science:
- Gynecology
- Reproductive Health
- Pathology
Background:
- Adenomyosis was historically underdiagnosed due to limited understanding of its causes and symptoms.
- Pre-operative diagnosis of adenomyosis presented significant challenges, often leading to its identification only after hysterectomy.
Purpose of the Study:
- To investigate potential risk factors associated with adenomyosis.
- To evaluate the correlation between various lifestyle and reproductive factors and the occurrence of adenomyosis.
Main Methods:
- A cross-sectional study involving 160 women who underwent hysterectomy between March 2010 and January 2012.
- Data collection included clinical symptoms, menstrual and reproductive history, contraception use, and smoking habits.
- Adenomyosis diagnosis was confirmed through pathological examination of hysterectomy specimens.
Main Results:
- Adenomyosis was diagnosed in 43.1% of the studied women.
- Risk factors identified included multiparity (OR 1.8), previous spontaneous abortion (OR 1.4), and prior dilatation and curettage (OR 1.9).
- Chronic smoking, particularly for over 10 years (OR 3.6), and irregular menstrual cycles (OR 1.7) were also associated with increased adenomyosis risk.
Conclusions:
- Multiparity, history of abortion, dilatation and curettage, chronic smoking, and irregular menstrual cycles are significant risk factors for adenomyosis.
- Further large-scale, population-based prospective epidemiological studies are necessary to elucidate the aetiopathology and clinical manifestations of adenomyosis.
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