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Related Experiment Video

Updated: May 15, 2026

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis

Published on: July 11, 2013

Persistent polymorphous light eruption after ultraviolet A1 phototherapy.

Mohammed I Aljasser¹, Harvey Lui, Nigel J Ball

¹Department of Dermatology and Skin Science, University of British Columbia, Photomedicine Institute, Vancouver Costal Health Research Institute, Vancouver, British Columbia, Canada.

Photodermatology, Photoimmunology & Photomedicine

|January 4, 2013

Summary

This summary is machine-generated.

Polymorphous light eruption (PMLE) is a common sun-induced rash. A case study details a persistent PMLE eruption lasting five weeks after ultraviolet A1 therapy.

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Area of Science:

Dermatology
Photomedicine

Background:

Polymorphous light eruption (PMLE) is the most common photodermatosis.
It presents as a pruritic eruption following ultraviolet radiation exposure.
PMLE typically resolves within two weeks without further UV exposure.

Observation:

PMLE is a known side effect of ultraviolet A1 (UVA1) therapy.
However, the eruption's characteristics, particularly its resolution time post-treatment, remain undescribed.
A case involved a 37-year-old female with persistent PMLE.

Findings:

The patient developed an unusually persistent PMLE.
The eruption lasted for five weeks after UVA1 phototherapy completion.
This duration significantly exceeds the typical resolution time for PMLE.

Implications:

This case highlights a prolonged PMLE reaction to UVA1 therapy.
Further research is needed to understand the characteristics and management of persistent PMLE post-phototherapy.
Clinicians should be aware of potential prolonged reactions to UVA1 therapy.