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A graphene oxide-photosensitizer complex as an enzyme-activatable theranostic agent
Youngnam Cho1, Hyunjin Kim, Yongdoo Choi
1Molecular Imaging & Therapy Branch, National Cancer Center, 323 Ilsan-ro, Goyang-si, Gyeonggi-do 410-769, Korea.
Chemical Communications (Cambridge, England)
|January 4, 2013
Abstract:
The development of a target-activatable "smart" platform with high-affinity and specificity is of great importance for a wide range of biomedical applications. Here, we attempted to develop a new enzyme-activatable graphene oxide-photosensitizer complex as a biologically tunable theranostic agent, making it promising for near-infrared (NIR) fluorescence imaging and photo-induced cancer therapy.
