Related Experiment Video
Updated: May 15, 2026

Techniques of Endoscopic Ossiculoplasty
Published on: January 26, 2024
The use of bone cement for ossicular chain defects
M Tayyar Kalcioglu1, Mehmet Tan, Jelle Fleerakkers
1Department of Otolaryngology, Istanbul Medeniyet University Medical Faculty, Istanbul, Turkey, mtkalcioglu@hotmail.com.
Bone cement effectively reconstructs ossicular chain defects, significantly improving hearing outcomes. This cost-effective material aids in procedures like incudostapedial re-bridging and interposition, offering a viable surgical solution.
Area of Science:
- Otolaryngology
- Audiology
- Biomaterials
Background:
- Ossicular chain defects can result from trauma or chronic otitis media, leading to conductive hearing loss.
- Traditional reconstruction methods may be complex or costly.
- Bone cement presents a potentially simpler and more economical alternative for ossicular reconstruction.
Purpose of the Study:
- To evaluate the audiologic outcomes of ossicular chain reconstruction using bone cement.
- To assess the efficacy of bone cement in different types of ossicular defects.
Main Methods:
- A retrospective study analyzing 120 patients with ossicular chain defects.
- Three groups were defined based on the type of reconstruction: ossiculoplasty, incus interposition, and total ossicular replacement with reshaped incus.
- Bone cement was used as a fixator in all groups. Preoperative and postoperative pure-tone audiometry were compared.
Main Results:
- Significant hearing improvement was observed across all three groups (p < 0.001).
- Mean air-bone gaps improved from 34.8 to 15.6 dB (Group 1), 35 to 18.4 dB (Group 2), and 43.4 to 19.8 dB (Group 3).
- Postoperative air-bone gaps ≤20 dB were achieved in 76% (Group 1), 64% (Group 2), and 46% (Group 3) of patients.
Conclusions:
- Bone cement is an effective and economical option for specific ossicular chain reconstructions, including incudostapedial re-bridging.
- It serves as a reliable fixator for interposed incus and reshaped incus prostheses, preventing displacement.
- Bone cement offers a valuable solution for improving hearing in patients with various ossicular defects.
More Related Videos
06:05Integrated Bone Formation Through In Vivo Endochondral Ossification Using Mesenchymal Stem Cells
Published on: July 14, 2023
07:35Creating Rigidly Stabilized Fractures for Assessing Intramembranous Ossification, Distraction Osteogenesis, or Healing of Critical Sized Defects
Published on: April 11, 2012
Related Concept Videos
Fractures: Bone Repair
Minor fractures with no bone displacement are treated by immobilizing the fractured bone using a cast or splint. However, in the case of fractures with displaced bones, the broken bones are repositioned before immobilization to ensure successful healing without deformation and loss of function. The realignment of fractured bone ends is performed through a process called reduction. If the procedure...
Bone Formation by Intramembranous Ossification
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Formation by Endochondral Ossification
Bone Remodeling and Repair
Bone as Supporting Connective Tissue
Bone Matrix
Bone, or osseous tissue, is a connective tissue that has a large amount of two different types of matrix material. The organic matrix is similar to the matrix material found in other connective tissues, including some amount of collagen and elastic fibers. This gives strength and flexibility to the tissue. The inorganic matrix consists of mineral salts— mostly calcium salts— that give the...
Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...